Jonathan Young,Barbara Czako,Michael Altman,David Guerin,Michelle Martinez,Alexey Rivkin,Kevin Wilson,Kathryn Lipford,Catherine White,Laura Surdi,Stephanie Chichetti,Matthew H. Daniels,Sean P. Ahearn
申请号:
US13517321
公开号:
US20120264735A1
申请日:
2010.12.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to pyridazin-4(1H)-one derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.