An orthopedic insole capable of being inserted into a shoe or the like for relieving and/or treating skin disorders and/or calluses and/or metatarsal pain comprises at least one semi-rigid corrective element capable of producing an inner metatarsal support, over the rear portion of the head of the first metatarsal, and/or a median metatarsal support, over the rear portion of the second and/or third and/or fourth metatarsal head, and/or an external metatarsal support, over the rear portion of the fifth metatarsal head.