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METHODS AND COMPOUNDS FOR REDUCING THREONYL-tRNA SYNTHETASE ACTIVITY
专利权人:
发明人:
Christopher Francklyn,Karen M. Lounsbury,Jason Botten
申请号:
US14416356
公开号:
US20150210997A1
申请日:
2013.07.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention includes, in part, methods and compounds for treating diseases and conditions characterized by elevated threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is elevated as compared to normal. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess a treatment for a disease or condition characterized by elevated TARS activity.
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