Ronit Sverdlov;Veerle Bieghs;Patrick Johannes Jacobus Van Gorp
发明人:
Ronit Sverdlov,Veerle Bieghs,Patrick Johannes Jacobus Van Gorp
申请号:
US13814838
公开号:
US20130184246A1
申请日:
2011.07.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention is in the field of medical treatments of liver disease, in particular, non-alcoholic fatty liver diseases, such as non-alcoholic steatohepatitis. The invention provides a composition comprising an effective amount of a compound capable of increasing the intracellular level of 27-hydroxycholesterol for the treatment of liver inflammation in fatty liver disease. It also provides a method of reducing liver inflammation in a patient with non-alcoholic fatty liver disease by administering an effective amount of 27-hydroxycholesterol.