A nerve stimulation appliance is described which has a first stimulator (11), which is designed to trigger a first stimulus in a nerve fibre of a nerve of a human or mammal, which stimulus propagates in a first direction in the nerve fibre, a second stimulator (12), which is designed to trigger a second stimulus in the nerve fibre, which stimulus propagates in the nerve fibre in a second direction counter to the first direction, wherein the first stimulator (11) and the second stimulator (12) are synchronized in such a way that the first stimulus and the second stimulus are generated within a predefined time window.