Martin Roelsgaard Jakobsen,Søren Riis Paludan,Kasper Lisager Jønsson
申请号:
US16323949
公开号:
US20190292236A1
申请日:
2017.08.09
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Compounds capable of mimicking the pyrin-domain of IFI16 is provided together with compounds capable of binding to the pyrin-domain of IFI16 or a fragment thereof as well as their uses in medicine. Specifically, the compounds are provided for use in the treatment of disorders associated with STING activity, including cancer and immuno-deficient or auto-immune disorders.