VERSTÄRKER FÜR T-ZELLEN ODER B-ZELLEN MIT GEDÄCHTNISFUNKTION, INHIBITOR EINES BÖSARTIGEN TUMORREZIDIVS UND INDUKTOR ZUM INDUZIEREN EINER GEDÄCHTNISFUNKTION IN T-ZELLEN ODER B-ZELLEN
Yamaguchi University;National University Corporation Tottori University
发明人:
申请号：
EP18866437.9
公开号：
EP3695846A1
申请日:
2018.10.09
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
An object of the present invention is to provide an enhancer for endogenous T-cells or B-cells having a memory function and a malignant tumor recurrence inhibitor in order to continue to reject malignant tumor over a long period of time. An enhancer for T-cells or B-cells having a memory function in an administration subject, comprising a nucleic acid delivery vehicle, a nucleic acid encoding interleukin-7 (IL-7), and a nucleic acid encoding chemokine (C-C motif) ligand 19 (CCL19), and an inducer for inducing a memory function in T-cells or B-cells in an administration subject, are prepared. Also, a malignant tumor recurrence inhibitor comprising a nucleic acid delivery vehicle, a nucleic acid encoding interleukin-7 (IL-7), and a nucleic acid encoding CCL19, is prepared.
