A fiber membrane with hollow structure is applied for a plasma separation apparatus. The plasma separation apparatus includes: a column and a hollow fiber membrane tube bundle is disposed within the column, the characteristic is in that: the hollow fiber membrane tube bundle is constituted by a plurality of fiber membranes with hollow structure, each plurality of fiber membranes with hollow structure is composed by polyester resin and a modified material, in which each plurality of fiber membranes with hollow structure having a smoth surface, by using the modified material to modify the surface of the fiber membrane with hollow structure that is provided for contacting the blood, such that the fiber membrane with hollow structure having a smooth surface to reduce the damage of the blood cell caused by the friction when the blood flow in the fiber membrane with hollow structure.一種具有中空結構的纖維膜的血漿分離裝置,血漿分離裝置包括管柱及容置於管柱內的中空纖維膜管束,其特徵在於:中空纖維膜管束由多條具有中空結構的纖維膜構成,且每一條具有中空結構的纖維膜由聚碸系樹脂及改質材料所構成,其中,每一條具有中空結構的纖維膜具有光滑表面,藉由改質材料用以對具有中空結構的纖維膜中,與血液接觸面的表層進行改質,使得具有中空結構的纖維膜具有光滑順暢的表面,可以降低血液在中空結構的纖維膜的流動中,因摩擦造成的血球細胞損傷。14‧‧‧中空纖維膜管束142‧‧‧纖維膜144‧‧‧中空結構
