Show-Li Chen,Hsin-Hsiung Chen,Kuan-Liang Lin,Wan-Lun Yan
申请号：
US13689472
公开号：
US20130081148A1
申请日:
2012.11.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention directs to a transgenic NRIP knockout mouse, the genome of which is manipulated to comprise a disruption of a nuclear receptor interaction protein (NRIP) gene, wherein the NRIP gene is disrupted by deletion of exon 2, the mouse exhibits a phenotype comprising abnormal muscular function. The present invention also directs to a method for making a transgenic NRIP knockout mouse whose genome comprises a homozygous disruption of the NRIP gene, the mouse exhibits abnormal muscular function.
