The present disclosure relates to a filter apparatus having a cylindrical housing (2) and a plurality of hollow fibers (3), with the hollow fibers being combined to form a bundle in the housing and being embedded and held in each case at the end sides in a moulding compound, and wherein the filtrate space is filled with particles (4) of a chemically or physically active substance. The invention furthermore relates to a method for the manufacture of such filter apparatus, to the use of the filter apparatus in medical, chemical and/or biotechnological applications, and to an apparatus and its use for the manufacture of the filter apparatus.