Philipp Hadwiger,Torsten Hoffmann,Kerstin Jahn-Hofmann,Eric A. Kitas,David L. Lewis,Peter Mohr,Hans Martin Mueller,Guenther Ott,Ingo Roehl,David B. Rozema
申请号：
US13917493
公开号：
US09198947B2
申请日:
2013.06.13
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides use of novel compounds for delivery of nucleic acids, and conjugates of these compounds with nucleic acids. Further novel design criteria for chemically stabilized siRNA particular useful when covalently attached to said compounds and co-administered with a delivery polymer to achieve mRNA knock down in vivo are disclosed therein.
