KOBOLD, SEBASTIAN;KOBOLD; SEBASTIAN;ENDRES, STEFAN
发明人:
KOBOLD, SEBASTIAN,ENDRES, STEFAN
申请号：
CA2989949
公开号：
CA2989949A1
申请日:
2016.06.20
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to PD-1-CD28 fusion proteins, nucleic acidmolecules, vectors, transduced cells carryingnucleic acid molecules or vectors of the present invention or expressing thefusion proteins of the present invention, methods andkits comprising the nucleic acid molecules, vectors and/or the fusion proteinsof the present invention. The invention also providesthe use of said transduced cells in a method for the treatment of particulardiseases as well as a pharmaceutical composition/medicamentcomprising said transduced cells expressing the fusion proteins of the presentinvention for use in a method of treating of diseases,in particular in the medical intervention of diseases characterized by PD-L1and/or PD-L2 expression.
