YAN, SHUNQI,WANG, LONGCHENG,FRYE, LEAH LYNN,CHEN, WEI,LOURY, DAVID J.
申请号：
CA2940039
公开号：
CA2940039A1
申请日:
2013.01.30
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosinekinase (Btk).Also described are irreversible inhibitors of Btk. In addition, reversibleinhibitors of Btk are alsodescribed. Also disclosed are pharmaceutical compositions that include thecompounds. Methodsof using the Btk inhibitors are disclosed, alone or in combination with othertherapeutic agents,for the treatment of autoimmune diseases or conditions, heteroimmune diseasesor conditions,cancer, including lymphoma, and inflammatory diseases or conditions.
