This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells, and combinations of T cell activating agents and/or an immune checkpoint inhibitors with and without peptides and peptidimimetics. The invention compounds and combinations can be used to inhibit cell growth, such as treat a tumor or cancer.本發明提供可用於治療細胞增殖病症(例如與良性及惡性腫瘤細胞相關之彼等)之化合物(包括肽及擬肽),及有及沒有肽及擬肽之T細胞活化劑及/或免疫查核點抑制劑之組合。本發明化合物及組合可用於抑制細胞生長,例如治療腫瘤或癌症。