Purdue Research Foundation;DePuy Synthes Products, Inc.
发明人:
Perla Venu,Prasanna Malaviya,Thomas J. Webster
申请号:
US14603080
公开号:
US09498218B2
申请日:
2015.01.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein the porous region exhibits a nano-textured surface, and a biocompatible polymer matrix coating the nano-textured surface. The polymer matrix coating comprises a naturally occurring extracellular matrix with biocompatible inorganic materials distributed within the matrix, or a biocompatible polymer and an osteo-inductive agent.