The present invention provides a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ. ID. NO:1, SEQ. ID. NO:2 and SEQ. ID. NO:7. Described are pharmaceutical compositions for the treatment of inflammatory conditions, as well as methods of treatment thereof, comprising as active agent said AChE antisense oligonucleotides.Linvention concerne une nouvelle utilisation des oligonucléotides antisens AChE comme agents anti-inflammatoires ces oligonucléotides correspondant préférablement aux séquences:SEQ. ID. NO:1, SEQ. ID. NO:2 et SEQ. ID. NO:7. Linvention décrit en outre des compositions pharmaceutiques destinées au traitement des états inflammatoires, ainsi que des méthodes de traitement de ces états, qui contiennent comme principe actif lesdits oligonucléotides antisens AChE.
