The present invention provide a method for fabricating a polysaccharide-based, dissolvable microneedle-based array, wherein the polysaccharide-based microneedle is made of a combination of 30-70% carboxymethyl cellulose (CMC) and 30-70% dextrin (DEX).本發明提供一種製造多醣系可溶解微針系陣列之方法,其中多醣系微針由30至70%的羧甲基纖維素(CMC)與30至70%的糊精(DEX)的組合而製成。