methods for treating or preventing cancer, for inhibiting a pim kinase, and for making a compound, compound, pharmaceutical composition, and use of a compound
James Edward Dowling,Jon Read,Leslie Dakin,Michelle Lamb,Qibin Su,Xiaolan Zheng
申请号：
BRPI0914599
公开号：
BRPI0914599A2
申请日:
2009.07.02
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.
