PROBLEM TO BE SOLVED: To provide a method for the treatment of imatinib resistant leukemia.SOLUTION: The present invention provides a pharmaceutical composition comprising a therapeutically effective amount of 4-[(2,4-Dichloro-5-methoxy phenyl) amino]-6-methoxy-7-[3-(4-methyl-1 -piperazinyl) propoxy]-3 quinolinecarbonitrile, represented by the following formula.SELECTED DRAWING: None【課題】イマチニブ耐性白血病の処置のための方法の提供。【解決手段】治療上有効な量の下記式で表される、4-[(2,4-ジクロロ-5-メトキシ-フェニル)アミノ]-6-メトキシ-7-[3-(4-メチル-1-ピペラジニル)プロポキシ]-3-キノリンカルボニトリルを含む医薬組成物。【選択図】なし