Regine Sitruk-Ware;Michael Maria Helmut Schumacher;Said Ghandour;Abdelmouman Ghoumari;Bartosz Bielecki;Rashad Hussain
发明人:
Regine Sitruk-Ware,Michael Maria Helmut Schumacher,Abdelmouman Ghoumari,Said Ghandour,Rashad Hussain,Bartosz Bielecki
申请号:
US14005690
公开号:
US20140011791A1
申请日:
2012.03.22
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Methods for effective remyelination in patients are disclosed comprising treating the patient with an androgen receptor ligand which exerts binding to androgen receptors and elicits androgen-receptor-induced biological responses at a dosage sufficient to induce remyelination. The androgen compound preferably comprises MENT in an androgen targeting both androgen and estrogen receptors, and the methods include combining the androgen compound with a progestin compound in order to provide both contraception in men and treatment for neurodegeneration.