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酪氨酸蛋白激酶抑制劑
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
DOMINIQUE, Romyr,KONG, Norman,LOU, Yan,LOPEZTAPIA, Francisco, Javier,SO, Sung-Sau
申请号:
HK16114476.6
公开号:
HK1226070A
申请日:
2016.12.20
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
This application discloses compounds according to generic Formula (I): wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are useful for the treatment of oncological, auto-immune, and inflammatory diseases caused by aberrant B-cell activation. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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