A system and method are provided to deliver interleaved stimulation to nerve tissue of interest. The system and method comprises an array of stimulation electrodes. The array is configured to be implanted proximate to nerve tissue of interest. An implantable medical device (IMD) is coupled to the array. The IMD includes memory storing a composite resultant pulse (CRP) sequence comprising first and second component sequences of first and second resultant pulse trains, respectively. One or more pulses from at least one of the first or second component sequences are temporally shifted relative to a corresponding target component sequence. The IMD further comprises a pulse generating circuit and switching circuit coupled to an output of the pulse generating circuit and the array. The switching circuit is configured to connect the pulse generating circuit to different combinations of the electrodes. The IMD further comprises a processor, configured to execute program instructions stored in the memory, directs the pulse generating circuit to generate the CRP sequence and manages the switching circuit to deliver the pulses of the first and second component sequences, in an interleaved manner, to first and second electrode combinations, respectively.
