This invention relates to a pharmaceutical composition comprising or consisting essentially of the phytocannabinoids cannabidivarin (CBDV)and cannabidiol (CBD). The composition is particularly safe and efficacious for use in the treatment of neurological conditions, characterized by hyper-excitability of the central nervous system, convulsions or seizures such as occur in epilepsy.Preferably the CBDV and the CBD are present with at least one non-cannabinoid component of cannabis such as one or more terpenes or a terpene fraction. More particularly the composition further comprises one or more cannabichromene type compounds. Particularly cannabichromene propyl variant (CBCV) and / or cannabichromene (CBC).More particularly still the composition is absent or substantially absent of other cannabinoids, including in particular tetrahydrocannabinol (THC) and tetrahydrocannabivarin (THCV), which would normally be present in significant amounts in cannabis chemotypes bred to contain a significant amount of CBDV and / or CBD.本發明係有關於含植物大麻素次大麻二酚(CBDV)及大麻二酚(CBD)或由其等所組成之藥學組成物。該組成物特別可安全且有效地用以治療，諸如發生在癲癇之其特徵為中樞神經系之過度刺激感受性、抽搐或癲癇發作的神經性病症。該CBDV及CBD較佳與大麻之至少一非大麻素組份(諸如一或多種萜類或一萜溶離份)一起存在。該組成物更佳進一步包含一或多種大麻色烯類型化合物。較佳為大麻色烯丙基變體(CBCV)及/或大麻色烯(CBC)。該組成物又更佳不含或實質上不含其它大麻素，這些其它大麻素尤其包括通常大量存在於大麻化學類型培養物內以含有大量CBDV及/或CBD之四氫大麻酚(THC)及四氫次大麻酚(THCV)。
