HIV-1 integrase derived stimulatory peptides interfering with integrase—Rev protein binding

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专利权人:

Assaf Friedler;Zvi Hayouka;Abraham Loyter;Aviad Levin

发明人:

Aviad Levin,Zvi Hayouka,Assaf Friedler,Abraham Loyter

申请号：

US13122548

公开号：

US09163067B2

申请日:

2009.10.01

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Isolated peptides comprising sequences derived from the protein integrase of HIV-1, as well as their analogs, mixtures, conjugates with permeability enhancing moieties, and pharmaceutical compositions are disclosed. The peptides and compositions are capable of selectively killing HIV-1 infected cells and are used in treatment of HIV infection and AIDS.

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