Oliver Plettenburg;Armin Hofmeister;Jean-Michel Altenburger;Matthias Loehn;Dieter Kadereit;Joachim Brendel
发明人:
Oliver Plettenburg,Armin Hofmeister,Dieter Kadereit,Joachim Brendel,Matthias Loehn,Jean-Michel Altenburger
申请号:
US12019799
公开号:
US08609691B2
申请日:
2008.01.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to 6-cyclohexylamine-substituted isoquinolone derivatives of the formula (I)or isoquinoline derivatives of the formula (I′)useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.