Claudia Cabella,Lara Caminiti,Sonia Colombo Serra,Pernille Rose Jensen,Magnus Karlsson,Mathilde H. Lerche,Luigi Miragoli,Luisa Poggi,Fabio Tedoldi,Luca Venturi
申请号：
US14437521
公开号：
US20150273086A1
申请日:
2013.10.24
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Hyperpolarized 1-13C-2-oxoglutarate as contrast agent in 13C Magnetic Resonance diagnostic technique (13C-MRI) for use in the diagnosis of cancer. In particular, upon administration of said 1-13C-2-oxoglutarate, signals of 1-13C-glutamate are detected. More in particular, different MR signals from 13C nuclei are detected and compared, said comparison being useful to determine a difference between tumor and non-tumor tissues, to determine the aggressiveness of a tumor or the efficacy of an anti-tumor therapy.
