Various techniques for providing a low leakage electrostatic discharge (ESD) structure for non-contact bio-signal sensors are disclosed. In some embodiments, a low leakage ESD structure for a capacitive bio-sensor includes a unity gain buffer, and an ESD protection circuit connected to the unity gain buffer, in which the ESD protection circuit includes a diode connected across an input and an output of the unity gain buffer, and in which a voltage range for the ESD protection circuit is configurable.