Provided are aqueous oral compositions comprising a cationic steroidal compound/ceragenin and a quaternary ammonium compound. A preferred cationic steroidal compound/ceragenin is a compound of general formula (I). A preferred quaternary ammonium compound is cetylpyridinium chloride. Further provided is the use of cationic steroidal compounds/ceragenins to treat ginigivitis, periodontitis, dental caries and oral malodour.