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method for the synthesis of n- (phosphonomethyl) glycine or one of its derivatives selected from the group consisting of their salts, phosphonate esters and phosphonate ester salts
专利权人:
STRAITMARK HOLDING AG
发明人:
FRÉDÉRIC BRUYNEEL,PATRICK NOTTÉ,SEBASTIAN BURCK
申请号:
BR112015000995
公开号:
BR112015000995A2
申请日:
2013.07.17
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
Abstract Method for the Synthesis of n- (phosphonomethyl) Glycine or one of its derivatives selected from the group consisting of their salts, their phosphonate esters and their phosphonate ester salts The present invention relates to a method for the synthesis of n- (phosphonomethyl) glycine or one of its derivatives selected from the group consisting of their salts, their phosphonate esters, or their phosphonate ester salts which includes the steps of: • a) forming, in the presence of an acid catalyst, a reaction mixture comprising 2,5-diketopiperazine, formaldehyde and a compound comprising one or more chemical portions of pop anhydride, said chemical portions having an oxidizing p-atom (+ iii ) and the other oxidizing p-atom (+ iii) or (+ v), form?,? '- bisphosphonomethyl-2,5-diketopiperazine, its mono to tetraphonate esters, the dehydrated forms of?,? '- bisphosphonomethyl-2,5-diketopiperazine and the esters of and phosphonate of its dehydrated forms; B) hydrolyzing said n, n'-bisphosphonomethyl-2,5-diketopiperazine, its dehydrated forms or its phosphonate esters to obtain n- (phosphonomethyl) glycine or one of its derivatives selected from the group consisting of their salts , their phosphonate esters and their phosphonate ester salts.resumo método para a síntese de n-(fosfonometil)glicina ou um de seus derivados selecionados a partir do grupo que consiste em seus sais, seus ésteres de fosfonato e seus sais de éster de fosfonato a presente invenção refere-se a um método para a síntese de n-(fosfonometil)glicina ou um de seus derivados selecionados a partir do grupo que consiste em seus sais, seus ésteres de fosfonato, ou seus sais de éster de fosfonato que inclui as etapas de: • a) formar, na presença de um catalisador ácido, uma mistura de reação que compreende 2,5-dicetopiperazina, formaldeído e um composto que compreende uma ou mais porções químicas de anidrido de p-o-p, sendo que as ditas porções químicas têm um átomo de p no estado de oxidação (+ iii) e o
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