The invention relates to the compounds of formula II or their pharmaceutical acceptable salts as well as polymorphs solvates enantiomers stereoisomers and hydrates thereof. The invention further relates to pharmaceutical compositions comprising an effective amount of compounds of formula II and methods for treating or preventing multiple sclerosis. The compositions may be formulated for oral buccal rectal topical transdermal transmucosal intravenous or parenteral administration as a syrup or for injection. Such compositions may be used in the treatment of neurodegenerative diseases and other inflammatory diseases.
