UNIVERSITE PARIS DIDEROT - PARIS 7;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);DAVID, BERTRAND;PETITE, HERVE;MYRTIL, VALENTIN
发明人:
DAVID, BERTRAND,PETITE, HERVE,MYRTIL, VALENTIN
申请号:
WO2008FR00846
公开号:
WO2009010661(A3)
申请日:
2008.06.18
申请国别(地区):
世界知识产权组织国际局
年份:
2009
代理人:
摘要:
The invention relates to a bone tissue culture method. Said method is of the type according to which: particles of a material compatible with the bone tissue are provided; stem cells of bone cells are provided; said particles are seeded with said bone cell stem cells; a nutritional fluid (31) is provided that contains nutritional elements for proliferating the bone cells; said nutritional elements are delivered to said bone cell stem cells via a flow of said nutritional fluid (31); and, according to the invention, said bone cell stem cells are held inside said flow so that said flow exerts mechanical stresses on said cells and so that said bone cells proliferate on said particles (35) to form implantable bone tissue granules. Then said implantable bone tissue granules are recovered in order to transplant them.