Liangxian Cao,Samit Hirawat,Langdon Miller,Thomas Davis,Marla L. Weetall
申请号：
US13274412
公开号：
US20120129841A1
申请日:
2011.10.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and compositions, and methods for the administration and use of those compounds. provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the treatment of solid tumor cancer, and in reducing serum, plasma, and/or tumor VEGF levels, are provided. In another aspect of the invention, methods are provided for the inhibition of VEGF production, the treatment of cancer, and the reduction of plasma and/or tumor VEGF levels, using the compounds of the invention.
