A method and apparatus for improvement of spatial resolution in molecular and radiological imaging is presented. System equipment includes bed with either flat or cylindrical detectors large detector arrays with collimator(s), lens(s), mirror(s) and/or shutter(s). This system utilizes magnification principles with large detector arrays. There is error reduction by reduction of non-collinearity error as seen in current PET scans by determination of the trajectory of the photons and accurate localization of the annihilation event of a positron. Additional error reduction of random coincidence and scatter coincidence is seen. Overall, this method and apparatus affords improved spatial resolution and higher efficiencies, which would allow for lower cost and dose reduction to the patient.
