NICHOLAS S. GRASMAN,OLIVER PETERMANN,MATTHIAS SPREHE,MEINOLF BRACKHAGEN,YONGFU LI,DAVID M. MEUNIER
申请号：
MX2015002427
公开号：
MX2015002427A
申请日:
2013.08.15
申请国别(地区):
MX
年份:
2015
代理人:
摘要：
A partially cross-linked esterified cellulose ether having A) groups of the formula -C(O) - R - COOA or a combination of aliphatic monovalent acyl groups and groups of the formula -C(O) - R - COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a molecular weight distribution such that [Wf(>；100k) - Wf(>；100k)XL] / Wf(>；100k)XL is at least 0.20, wherein Wf(>；100k) is the total weight fraction of the esterified cellulose ether that exceeds 100,000 g/mol, and Wf(>；100k)XL is the weight fraction that exceeds 100,000 g/mol of the methylated esterified cellulose ether is useful as enteric polymer for pharmaceutical dosage forms. A partially cross-linked esterified cellulose ether having A) groups of the formula -C(O) - R - COOA or a combination of aliphatic monovalent acyl groups and groups of the formula -C(O) - R - COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and B) having a molecular weight distribution such that [Wf(>；100k) - Wf(>；100k)XL] / Wf(>；100k)XL is at least 0.20, wherein Wf(>；100k) is the total weight fraction of the esterified cellulose ether that exceeds 100,000 g/mol, and Wf(>；100k)XL is the weight fraction that exceeds 100,000 g/mol of the methylated esterified cellulose ether is useful as enteric polymer for pharmaceutical dosage forms. A lubricating composition includes an (A) esterified copolymer comprising units (A1) derived from a vinyl monomer and units (A2) derived from a carboxylic acid monomer, the vinyl monomer comprising a vinyl aliphatic monomer, the carboxylic acid monomer comprising an ethylenically unsaturated carboxylic acid or derivative thereof, esterified with a primary alcohol； and (B) an oil of lubricating viscosity. The lubricating composition can provide a lubricant with at least one (or at least two, or all) of acceptable or improved HTHS, KV, shear stability, acceptable or improved viscosity in
