Pharmosa Biopharm Inc.;Pharmosa Therapeutics, Inc.
发明人:
Pei KAN,Yi Fong LIN,Ko Chieh CHEN
申请号：
US16568801
公开号：
US20200085741A1
申请日:
2019.09.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are pharmaceutical compositions containing at least one liposome, said liposome comprise an external lipid bilayer including at least one vesicle-forming phospholipid and less than 15 mole % of sterol； and an internal aqueous medium including a weak acid drug and weak acid salt. The pharmaceutical compositions reduce the burst release of the weak acid drug. Also provided is the use of the pharmaceutical composition disclosed herein to treat respiratory diseases and reduce the side effect of the weak acid drug.
