The present invention relates to a herbal composition for use in the prevention or treatment of a disease mediated by TNF-α. The present invention also provides a method for the preparation of the herbal composition and methods for using such herbal composition.本發明係相關於用於TNF-α媒介的疾病預防或治療之中藥組合物。本發明亦提供該中藥組合物的製備方法以及使用此類中藥組合物的方法。