In one aspect, methods of growing autologous biological tissue are described herein. In some embodiments, a method described herein comprises disposing a porous scaffold in a body cavity of a patient, wherein the scaffold comprises one or more biofactors comprising one or more chemokines that promote migration of autologous multipotent cells into the body cavity and/or one or more differentiation agents that promote differentiation of autologous multipotent cells into the autologous biological tissue. The body cavity can comprise a soft tissue cavity such as the peritoneal cavity. A method described herein can also comprise depositing the multipotent cells onto a surface of the scaffold and inducing differentiation of the multipotent cells on the surface of the scaffold to provide differentiated autologous tissue. Additionally, a method can further comprise growing the autologous biological tissue from the differentiated autologous tissue. Further, the autologous tissue may not be native to the body cavity.
