University of Florida Research Foundation; Incorporated
发明人:
Jeffrey S. Bartlett
申请号：
US16326488
公开号：
US20190381140A1
申请日:
2017.08.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Methods and compositions for treating symptoms of conditions such as but not limited to osteoarthritis and rheumatoid arthritis. The methods may feature direct intraarticular injection of a recombinant self-complementary adeno-associated virus (sc-rAAV) with a vector adapted to express a modified IL-1Ra peptide. The methods of the present invention may express a therapeutically effective amount of the modified IL-1Ra peptide so as to ameliorating symptoms associated with the condition being treated.
