WOMENS AND CHILDRENS HEALTH NETWORK INCORPORATED;WOMEN'S AND CHILDREN'S HEALTH NETWORK INCORPORATED;OMARI, Taher, Imad
发明人:
OMARI, Taher, Imad
申请号：
AUAU2011/001174
公开号：
WO2012/034168A1
申请日:
2011.09.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to methods for assessing swallowing motor function in a subject. The methods rely on obtaining intraluminal impedance and pressure measurements from the pharynx and/or esophagus of the subject during clearance of a bolus from the mouth and/or throat of the subject. The intraluminal impedance and pressure measurements are combined to derive a value for one or more pressure-flow variables in the pharynx and/or esophagus of the subject. The value of the one or more pressure-flow variables is compared to a predetermined pharyngeal and/or esophageal reference value for the one or more pressure-flow variables in order to provide an assessment of swallowing motor function in the subject. The intraluminal impedance and pressure measurements can also be combined to generate a swallow risk index for the subject or to generate an obstructive risk index for the subject based on a combination of a value of more than one pressure-flow variable in the pharynx and/or esophagus of the subject. In this way, swallowing motor function in the subject can be assessed by comparing the swallow risk index or obstructive risk index for the subject to a predetermined reference swallow index or predetermined reference obstructive index, respectively. Products which make use of these methods are also encompassed by the present invention.La présente invention porte sur des procédés d'évaluation de la fonction motrice de déglutition chez un sujet. Les procédés reposent sur l'obtention de mesures d'impédance et de pression intraluminales à partir du pharynx et/ou de l'œsophage du sujet durant la suppression d'un bolus de la bouche et/ou de la gorge du sujet. Les mesures d'impédance et de pression intraluminales sont combinées pour déduire une valeur pour une ou plusieurs variables pression-écoulement dans le pharynx et/ou l'œsophage du sujet. La valeur de la ou des variables pression-écoulement est comparée avec une valeur de référence de pharynx et/ou d'œsophage préd
