Disclosed are manual thrombectomy devices having a plurality of elastic wires to form one or more cages and/or soft brushes connected to a lumen shaft along a longitudinal direction to easily detach thrombi from a vessel wall by manually rotating the lumen shaft right and left. And without any extra inflow tube, the manual thrombectomy device has an aspiration lumen and an inflow lumen in one body of the lumen shaft not only for preventing occurrence of a vacuum or a low pressure state in the blood vessel due to the thrombi aspiration during operation, but also for cleaning the vessel wall through outflow holes and for excreting the thrombi through aspiration holes.