Ramot at Tel-Aviv University Ltd. ;The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
发明人:
ROSIN-ARBESFELD Rina,SIMAN-TOV Ronen
申请号:
US201615739857
公开号:
US2018360025(A1)
申请日:
2016.07.21
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
An ex-vivo method of increasing survival of red blood cells (RBCs) is provided. The method comprising contacting the RBCs with an activator of the non-canonical Wnt pathway, which results in actin polymerization, thereby increasing survival of red blood cells (RBCs). Also provided is a method of storing RBCs and treating a medical condition associated with RBC cytoskeleton/membrane disease.