Saul Tzipori;John E. Herrmann;Boris R. Belitsky;Abraham L. Sonenshein
发明人:
John E. Herrmann,Boris R. Belitsky,Abraham L. Sonenshein,Saul Tzipori
申请号：
US12987280
公开号：
US09610333B2
申请日:
2011.01.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods for immunizing a subject to an antigen of an infectious agent, a tumor, or an allergen are provided, using vegetative cytoplasmic expression of the antigen or spore surface display of the antigen, and contacting the subject with a composition including a spore or a vegetative cell or both with or without an adjuvant. Also included are thermally-stable vaccine compositions using the method described above and kits including the compositions.
