Miraglia, Niccolò,Bianchi, Davide,Valoti, Ermanno,Trentin, Antonella,Trilli, Antonio,Busiello, Immacolata,Agostinetto, Marco,Bazza, Paola,Valetti, Marco
申请号：
HRP20160773
公开号：
HRP20160773T1
申请日:
2016.07.01
申请国别(地区):
HR
年份:
2016
代理人:
摘要：
Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS) produced by chemical sulphation and subsequent depolymerisation of a non-sulphated chondroitin backbone obtained with biotechnology techniques. The CS described is substantially monosulphated, mainly at the 6-position, with very little sulphation at the 4-position, and with a mono/disulphated disaccharide ratio and charge density similar to those of natural CS. Said biotechnological chondroitin 6-sulphate (C6S) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes.
