PROBLEM TO BE SOLVED: To provide compositions for treatment of papulopustular rosacea, the treatment being safer and more effective than conventional treatment such as topical metronidazole.SOLUTION: A topical composition comprises about 1 wt.% of ivermectin, and a pharmaceutically acceptable carrier comprising a fatty substance such as cetyl alcohol, a surfactant such as Steareth-20, a solvent and/or propenetrating agent such as propylene glycol, a gelling agent such as a carbomer, and water.SELECTED DRAWING: None【課題】丘疹膿疱性の酒さの治療に於いて、局所メトロニダゾールのような従来の治療法よりも安全かつ効果的な治療のための組成物の提供。【解決手段】約1重量%のイベルメクチンと薬学上許容されるセチルアルコール等の脂肪性物質、ステアレスー20等の界面活性剤、プロピレングリコール等の溶剤及び/又は浸透増強剤、カルボマー等のゲル化剤及び水などからなる担体を含む局所用組成物。【選択図】なし