A Neonauclea reticulata leaf extract of which the absorption spectroscopy includes peaks within the following wave ranges: from 265 to 295 nm and from 305 to 335 nm. The extract is useful for anti-oxidation, inhibiting the activity of matrix metalloproteinases (MMPs), inhibiting the expression of matrix metalloproteinase, and/or inhibiting the phosphorylation of mitogen-activated protein kinase (MAP Kinase) pathway.一種欖仁舅葉萃取物,其吸收光譜係包含以下波長範圍之吸收峰:265至295奈米及305至335奈米,該萃取物可用於抗氧化、抑制基質金屬蛋白酶活性、抑制基質金屬蛋白酶生成、及/或抑制有絲分裂原活化蛋白激酶途徑之磷酸化。