The invention relates to novel heterocyclic compounds of the formulain which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.本發明係關於新穎下式雜環族化合物其中所有變數均如本專利說明書中所定義,呈自由態形式或呈鹽形式,其製備,其醫藥用途,及包含彼等之藥劑。