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Organic amine salts of aminobenzoic acid derivatives and method for producing same
专利权人:
NISSAN CHEMICAL INDUSTRIES LTD.
发明人:
TAKEUCHI KAZUYA,ISHIDA MARIKO,YAMAMOTO MASAO,IWAMOTO SHUNSUKE,NAKANO SATOSHI
申请号:
NZ60929711
公开号:
NZ609297A
申请日:
2011.11.01
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed are salts of 3-{ [((2E)-2-{ 1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene} hydrazino)carbonothioyl]amino} benzoic acid, wherein said salt is an organic amine salt or a salt with quaternary ammonium cation. Salts of particular importance include salts where the organic amine or quaternary ammonium salt is an organic amine or quaternary ammonium salt having a hydroxy group such as ethanolamine, tromethamine or choline. Further disclosed is a crystalline tromethamine salt of 3-{ [((2E)-2-{ 1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene} hydrazino)carbonothioyl]amino} benzoic acid for use in medicine as a thrombopoietin receptor activator or a platelet increasing agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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