INC.;VENTIRX PHARMACEUTICALS;ARRAY BIOPHARMA;VENTIRX PHARMACEUTICALS, INC.
发明人:
HOWBERT, JAMES JEFFRY,HERSHBERG, ROBERT,BURGESS, LAURENCE E.,YANG, HONG WOON
申请号:
EP12734770
公开号:
EP2663550A4
申请日:
2012.01.12
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Provided are benzazepine derivatives useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The benzazepine derivatives have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.