DE MAN, ADRIANUS PETRUS ANTONIUS,UITDEHAAG, JOOST CORNELIS MARINUS,STERRENBURG, JAN GERARD,DE WIT, JOERI JOHANNES PETRUS,SEEGERS, NICOLE WILHELMINA CORNELIA,VAN DOORNMALEN, ANTONIUS MARIA,BUIJSMAN, RO
申请号:
CA3030220
公开号:
CA3030220A1
申请日:
2017.07.11
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to a compound of Formula I : Formula I, or pharmaceutically acceptable enantiomers, or salts thereof. The present invention also relates to the use of compounds of Formula (I) as selective inhibitors of tryptophan 2,3-dioxygenase. The invention also relates to the use of the compounds of Formula (I) for the treatment or prevention of cancer and central nervous system disease or disorder, either as a single agent or in combination with other therapies.