[PROBLEM]It is an object to provide a biological tissue fabrication information generating device that generates biological tissue fabrication information for fabrication of tissue imitative of the structure of the biological tissue of a patient, a biological tissue fabrication system that fabricates biological tissue based on biological tissue fabrication information, and a medical expense calculation system that calculates the medical expense of a patient receiving therapeutic graft of biological tissue.[SOLUTION MEANS]A biological tissue fabrication information generating device characterized in that it comprises structure information storage unit 10 that stores tissue structure information D1 indicating three-dimensional structure of biological tissue of patient Pt, and biological tissue fabrication information generator 11 that generates biological tissue fabrication information D3 in the form of information linking respective locations within biological tissue indicated by tissue structure information D1, and the types of cells that should be arranged at such respective locations, based on tissue structure information D1 and cell type information D4 for determining types of cells at respective locations in biological tissue indicated by tissue structure information D1.